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Characterisation and comparison of the chicken H1 RNA polymerase III promoter for short hairpin RNA expression

โœ Scribed by David M. Cummins; Scott G. Tyack; Timothy J. Doran


Book ID
116302615
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
764 KB
Volume
416
Category
Article
ISSN
0006-291X

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## Background The use of small interfering RNA (siRNA) molecules in animals to achieve double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful method of sequence-specific gene knockdown. As DNA-based expression of short hairpin RNA (shRNA) for RNAi may offer some advanta