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Comparison of bovine RNA polymerase III promoters for short hairpin RNA expression

โœ Scribed by L. S. Lambeth; T. G. Wise; R. J. Moore; M. S. Muralitharan; T. J. Doran


Book ID
108633374
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
578 KB
Volume
37
Category
Article
ISSN
0268-9146

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## Background The use of small interfering RNA (siRNA) molecules in animals to achieve double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful method of sequence-specific gene knockdown. As DNA-based expression of short hairpin RNA (shRNA) for RNAi may offer some advanta