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Characteristics of sinusoidal uptake and biliary excretion of cysteinyl leukotrienes in perfused rat liver

✍ Scribed by Matthias WETTSTEIN; Wolfgang GEROK; Dieter HÄUSSINGER


Book ID
115128000
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
550 KB
Volume
191
Category
Article
ISSN
1432-1327

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Hypoxia and CCI4-induced liver injury, b
✍ Matthias Wettstein; Wolfgang Gerok; Prof. Dr. Dieter Häussinger 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 796 KB

Uptake, metabolism and biliary elimination of infused cysteinyl leukotrienes were investigated in single-pass perfused rat liver. Hypoxia did not impair uptake of infused [3H]leukotriene C4, but inhibited biliary excretion of radioactivity by about 50% compared with normoxic control experiments. In