𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characteristics of a tumor cell line and virus derived from hamster tumors induced by rauscher leukemia virus-transformed hamster embryo cells

✍ Scribed by Johng Sik Rhim; R. J. Huebner; R. C. Ting; N. Wivel; W. Vass

Publisher
John Wiley and Sons
Year
1970
Tongue
French
Weight
884 KB
Volume
5
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A transplantable hamster tumor (RHT‐1) induced by Rauscher leukemia‐virus‐transformed hamster embryo cells was established in tissue culture, and its characteristics were studied. The tumor cell line also contained group‐specific complement‐fixing antigen and continuously released infectious virus. Electron microscope observation showed that this cell line contained C‐type particles. The virus derived from this line served as “helper virus” for a defective Moloney sarcoma virus (MSV) from a non‐infectious hamster tumor (HT‐1), and rescued infectious MSV by direct superinfection of the HT‐1 cells. This infectious MSV virus, which was identified as MSV (RLV) by the focus neutralization test, produced foci readily in both hamster embryo cells and NIH‐METC. Foci produced by this MSV (RLV) pseudotype in hamster embryo cells consisted largely of spindle‐shaped cells which stained vividly with acridine orange. Tumors were produced when cell‐free supernates of MSV (RLV)‐transformed hamster embryo cells, or the cells themselves, were injected into newborn mice. Tumors were also produced when transformed cells were injected into newborn hamsters.

📜 SIMILAR VOLUMES

Cell surface antigen induced by avian tu
Cell surface antigen induced by avian tumor viruses in hamster cells transformed by a temperature-sensitive mutant of rous sarcoma virus
✍ Michèle C. Aupoix; Jean-Michel Biquard; Annie Cachard 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 French ⚖ 414 KB 👁 1 views

## Abstract Hamster cells (BHK21/13) transformed at the permissive temperature by a temperature‐sensitive mutant (FU 19) of the Schmidt‐Ruppin strain of Rous sarcoma virus exhibited a temperature‐dependent expression of virus‐induced surface antigen (VISA) as assayed by mixed haemadsorption test. T

High resolution electrophoresis of extra
High resolution electrophoresis of extracts of a baby hamster kidney cell line before and after transformation by polyoma virus
✍ Thomas Marshall; Professor Albert L. Latner 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 642 KB

## Abstract The polypeptide patterns obtained following denaturation and high resolution two‐dimensional electrophoresis of proteins from baby hamster kidney cells before and after transformation by Polyoma virus have been compared by silver staining incorporating methylamine. The polypeptides were

Rescue of the genome of the defective mu
Rescue of the genome of the defective murine sarcoma virus from a non-producer hamster tumor cell line, pm-1, with murine and feline leukemia viruses as helpers
✍ C. Monti-Bragadin; K. Ulrich 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 French ⚖ 691 KB

## Abstract Some properties of a hamster tumor cell line, the PM‐1 cl 6 (PM‐1), derived from a hamster tumor induced by the Harvey murine sarcoma virus (H‐MuSV) are described. The PM‐1 cell line appears to be free of viruses of the murine leukemia‐sarcoma complex as tested by the absence of plaque

Clonal derivatives of a herpes type 2 tr
Clonal derivatives of a herpes type 2 transformed hamster cell line (333-8-9): Cytogenetic analysis, tumorigenicity and virus sequence detection
✍ Christine D. Copple; James K. McDougall 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 917 KB

## Abstract The characteristics of the Syrian hamster cell line (333‐8‐9), putatively transformed by herpes virus type 2 (HSV‐2), strain 333, have been examined. The line has been cloned and the clones characterized cytogenetically and morphologically. The original line and the clones have been ass

Transformation by inorganic arsenic comp
Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters
✍ Masayuki Takahashi; J. Carl Barrett; Takeki Tsutsui 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 294 KB

## Abstract Arsenic is a known human carcinogen, but little evidence exists for its carcinogenicity in animals. In order to investigate the ability of inorganic arsenics to transform normal cells into a neoplastic state, mass cultures of normal, diploid Syrian hamster embryo (SHE) cells exposed to