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Cell surface antigen induced by avian tumor viruses in hamster cells transformed by a temperature-sensitive mutant of rous sarcoma virus

✍ Scribed by Michèle C. Aupoix; Jean-Michel Biquard; Annie Cachard

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
414 KB
Volume
14
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Hamster cells (BHK21/13) transformed at the permissive temperature by a temperature‐sensitive mutant (FU 19) of the Schmidt‐Ruppin strain of Rous sarcoma virus exhibited a temperature‐dependent expression of virus‐induced surface antigen (VISA) as assayed by mixed haemadsorption test. This temperature‐dependence of VISA was not observed in cells transformed by the wild‐type virus (SR4), although the number of positive cells was reduced at the restrictive temperature (41° C) when compared to cells incubated at the permissive temperature (37° C). The relations between cell transformation and expression of VISA are discussed.

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Regulation of sugar transport in chick embryo fibroblasts and in fibroblasts transformed by a temperature-sensitive mutant of the rous sarcoma virus
✍ Rolf F. Kletzien; James F. Perdue 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

## Abstract The mode of induction of sugar transport by serum‐stimulation of growth and hexose‐starvation in chick embryo fibroblasts (CEF) has been studied using metabolic inhibitors. We have concluded from these studies that the sugar transport increases induced by serum‐stimulation are regulated