Changes in iron-regulatory gene expressi
Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson’s disease
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C.B. Carroll; M.-L. Zeissler; N. Chadborn; K. Gibson; G. Williams; J.P. Zajicek;
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Article
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2011
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Elsevier Science
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English
⚖ 918 KB
## Background: Neuronal iron accumulation is thought to be relevant to the pathogenesis of parkinson's disease (pd), although the mechanism remains elusive. we hypothesized that neuronal iron uptake may be stimulated by functional mitochondrial iron deficiency. ## Objective: To determine firstly