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Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease

✍ Scribed by Daniel J. Costello; Gerard W. O'Keeffe; Fiona M. Hurley; Aideen M. Sullivan

Book ID
119857654
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2012
Tongue
English
Weight
496 KB
Volume
16
Category
Article
ISSN
1582-1838

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## Background: Neuronal iron accumulation is thought to be relevant to the pathogenesis of parkinson's disease (pd), although the mechanism remains elusive. we hypothesized that neuronal iron uptake may be stimulated by functional mitochondrial iron deficiency. ## Objective: To determine firstly