Prevention of onset of Parkinson’s disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson’s disease
✍ Scribed by Koike, H; Ishida, A; Shimamura, M; Mizuno, S; Nakamura, T; Ogihara, T; Kaneda, Y; Morishita, R
- Book ID
- 110039860
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 244 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0969-7128
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Parkinson's disease (PD) is the second most common neurodegenerative disease. Although 10 gene loci have been identified to cause a Parkinsonian syndrome, these loci account only for a minority of PD patients. Large, systematic research programs are required to collect, store, and analy
Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects approximately 1,000,000 Americans. The cause of the disease remains unknown. The histopathological hallmarks of the disease are dopaminergic striatal insufficiency secondary to a loss of dopaminergic neurons in the sub
## Abstract A typical feature of Parkinson's disease is the progressive loss of dopaminergic neurons in the substantia nigra, in which inhibition of mitochondrial complex I activity may play an important role. Rotenone or 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) inhibit the mitochondrial