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CGC enantiomer separation on diluted cyclodextrin derivatives coated on fused silica columns

✍ Scribed by Schurig, Volker ;Jung, Martin ;Schmalzing, Dieter ;Schleimer, Martin ;Duvekot, Jan ;Buyten, Jan C. ;Peene, Jürgen A. ;Mussche, Philippe

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
368 KB
Volume
13
Category
Article
ISSN
0935-6304

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✦ Synopsis

Abstract

High‐resolution capillary gas chromatographic separation of enantiomers, belonging to different classes of compounds on cyclodextrin derivatives is described. The solutions of heptakis (2,3,6‐O‐trimethyl)‐β‐cyclodextrin (Phase I), heptakis (2,6‐O‐dimethyl‐3‐O‐trifluoro‐acetyl)‐β‐cyclodextrin (Phase II) and heptakis (2,6‐O‐dimethyl‐3‐O‐heptafluorobutyryl)‐β‐cyclodextrin (Phase III) in the moderately polar polysiioxane OV‐1701 were coated onto deactivated fused silica capillaries furnishing columns of high efficiency. The three phases show different enantioselectivities for various racemic mixtures.

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