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Ceramide induces cell cycle arrest and upregulates p27kip in nasopharyngeal carcinoma cells

โœ Scribed by Xiao-Feng Zhu; Zong-Chao Liu; Bin-Fen Xie; Gong-Kan Feng; Yi-Xin Zeng


Book ID
117467714
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
156 KB
Volume
193
Category
Article
ISSN
0304-3835

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## Abstract ฮฑโ€Lipoic acid is a naturallyโ€occurring coโ€factor found in a number of multiโ€enzyme complexes regulating metabolism. We report here that ฮฑโ€lipoic acid induces hyperacetylation of histones in vivo and has differential effects on the growth and viability of normal versus transformed cell l