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Cell cycle-independent upregulation of p27Kip1 by p21Waf1 in K562 cells

✍ Scribed by Steinman, Richard A; Lu, Yalin; Yaroslavskiy, Beatrice; Stehle, Christine

Book ID
110066043
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
212 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract __SDI1__ is an inhibitor of DNA synthesis that we isolated by expression screening cDNAs prepared from senescent, terminally nondividing human cells. Other groups then cloned this gene as a cyclin‐dependent kinase (cdk)‐interacting protein (CIP1, p21) that inhibits cdks; the gene was al