Centrosome biogenesis and function: centrosomics brings new understanding
✍ Scribed by Bettencourt-Dias, Mónica; Glover, David M.
- Book ID
- 109958770
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 726 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm2180
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Centrosomes nucleate microtubules that form the mitotic spindle and regulate the equal division of chromosomes during cell division. In cancer, centrosomes are often found amplified to greater than two per cell, and these tumor cells frequently have aneuploid genomes. In this review, we
## Abstract The centrosome is the main MT organizing center in animal cells, and has traditionally been regarded as essential for organization of the bipolar spindle that facilitates chromosome segregation during mitosis. Centrosomes are associated with the poles of the mitotic spindle, and several