RNA in centrosomes: Structure and possible functions
β Scribed by Konstantin Chichinadze, Ann Lazarashvili, Jaba Tkemaladze
- Book ID
- 118789274
- Publisher
- Springer Vienna
- Year
- 2012
- Tongue
- English
- Weight
- 179 KB
- Volume
- 250
- Category
- Article
- ISSN
- 0033-183X
No coin nor oath required. For personal study only.
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The centrosome found in animal cells is a complex and dynamic organelle that functions as the major microtubule organizing center. Structural studies over the past several decades have defined the primary structural features of the centrosome but recent studies are now beginning to reveal structural
## Abstract Centrosomes nucleate microtubules that form the mitotic spindle and regulate the equal division of chromosomes during cell division. In cancer, centrosomes are often found amplified to greater than two per cell, and these tumor cells frequently have aneuploid genomes. In this review, we