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Central Obesity, the Metabolic Syndrome, and Plasminogen Activator Inhibitor-1 in Young Adults

✍ Scribed by Susan J. Appel; Joanne S. Harrell; Marsha L. Davenport

Book ID
111359140
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
100 KB
Volume
17
Category
Article
ISSN
1041-2972

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## Abstract Plasminogen activator inhibitor‐1 (PAI‐1) is a physiological inhibitor of urokinase (uPA), a serine protease known to promote cell migration and invasion. Intuitively, increased levels of PAI‐1 should be beneficial in downregulating uPA activity, particularly in cancer. By contrast, in