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Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation

โœ Scribed by LD DeLeve


Book ID
118686420
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
301 KB
Volume
24
Category
Article
ISSN
0270-9139

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Cellular target of cyclophosphamide toxi
โœ L D DeLeve ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 302 KB

in hepatocytes, and that SEC glutathione (GSH) plays a ma-Hepatic venoocclusive disease (HVOD) is caused by jor role in detoxification. 10,11 Furthermore, the evidence sugthe disruption of the microcirculation by an as-yet ungests that profound depletion of SEC GSH might be the comknown mechanism. P