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Cells in cryptophycin-induced cell-cycle arrest are susceptible to apoptosis

✍ Scribed by David Kessel; Yu Luo


Book ID
117469762
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
264 KB
Volume
151
Category
Article
ISSN
0304-3835

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## Abstract 2‐Methoxyestradiol (2ME) is an endogenous metabolite with estrogen receptor‐independent anti‐tumor activity. The current study seeks to determine the mechanism of anti‐tumor activity of 2ME on human chondrosarcoma. 2ME caused a time‐ and dose‐dependent cytotoxity in chondrosarcoma cells