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Arecoline induced cell cycle arrest, apoptosis, and cytotoxicity to human endothelial cells

โœ Scribed by Tseng, Shuei-Kuen; Chang, Mei-Chi; Su, Cheng-Yao; Chi, Lin-Yang; Chang, Jenny Zwei-Ching; Tseng, Wan-Yu; Yeung, Sin-Yuet; Hsu, Ming-Lun; Jeng, Jiiang-Huei

Book ID
113053096
Publisher
Springer
Year
2011
Tongue
English
Weight
387 KB
Volume
16
Category
Article
ISSN
1432-6981

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## Abstract 2โ€Methoxyestradiol (2ME) is an endogenous metabolite with estrogen receptorโ€independent antiโ€tumor activity. The current study seeks to determine the mechanism of antiโ€tumor activity of 2ME on human chondrosarcoma. 2ME caused a timeโ€ and doseโ€dependent cytotoxity in chondrosarcoma cells