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Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP)

✍ Scribed by Hiroshi Sato; Takahisa Takino; Takeshi Kinoshita; Kazushi Imai; Yasunori Okada; William G. Stetler Stevenson; Motoharu Seiki


Book ID
115932346
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
384 KB
Volume
385
Category
Article
ISSN
0014-5793

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Involvement of membrane type 1-matrix me
✍ Masashi Kamioka; Toshiyuki Ishibashi; Hiroshi Ohkawara; Ryoji Nagai; Koichi Sugi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 807 KB

## Abstract An advanced glycation end products (AGE)/a receptor for AGE (RAGE) axis plays a key role in diabetic vascular complications. Membrane type 1‐matrix metalloproteinase (MT1‐MMP) has been shown to function not only as a proteolytic enzyme but also as a signaling molecule. In this study, we