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Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis

✍ Scribed by Susanne Petri; Mahmoud Kiaei; Maria Damiano; Andrew Hiller; Elizabeth Wille; Giovanni Manfredi; Noel Y. Calingasan; Hazel H. Szeto; M. Flint Beal


Book ID
111179709
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
285 KB
Volume
98
Category
Article
ISSN
0022-3042

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Therapeutic benefits of intrathecal prot
✍ Yasuyuki Ohta; Tatsushi Kamiya; Makiko Nagai; Tetsuya Nagata; Nobutoshi Morimoto πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 589 KB

## Abstract When fused with the protein transduction domain (PTD) derived from the human immunodeficiency virus TAT protein, proteins can cross the blood–brain barrier and cell membrane and transfer into several tissues, including the brain, making protein therapy feasible for various neurological