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Therapeutic Benefits of Putrescine-Modified Catalase in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis

✍ Scribed by Monica M. Reinholz; Carolin M. Merkle; Joseph F. Poduslo


Book ID
115607039
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
168 KB
Volume
159
Category
Article
ISSN
0014-4886

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## Abstract When fused with the protein transduction domain (PTD) derived from the human immunodeficiency virus TAT protein, proteins can cross the blood–brain barrier and cell membrane and transfer into several tissues, including the brain, making protein therapy feasible for various neurological