Cell-mediated cytotoxicity to SV40-specific tumour-associated antigens
✍ Scribed by TRINCHIERI, GIORGIO; ADEN, DAVID P.; KNOWLES, BARBARA B.
- Book ID
- 109699354
- Publisher
- Nature Publishing Group
- Year
- 1976
- Tongue
- English
- Weight
- 339 KB
- Volume
- 261
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/261312a0
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## Abstract The role of adherent phagocytic cells in an __in vitro__ secondary cytotoxic response against Simian virus 40 (SV40)‐induced tumor‐associated antigens was investigated. Spleen cells (responder cells), from mice primed with syngeneic SV40‐transformed cells, extensively depleted of macrop
## Abstract Specific secondary cytotoxic reactivity (as measured by ^51^Cr‐release assay) against SV 40‐induced tumor‐associated antigens was generated __in vitro__ in spleen cells of tumor‐free (BALB/c × C57 BL/6)F~1~ (CBF~1~) mice immunized against a syngeneic SV 40‐induced tumor of BALB/c origin