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Cell growth on immobilized cell growth factor. 6. Enhancement of fibroblast cell growth by immobilized insulin and/or fibronectin

✍ Scribed by Ito, Y. ;Inoue, M. ;Liu, S. Q. ;Imanishi, Y.

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
603 KB
Volume
27
Category
Article
ISSN
0021-9304

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✦ Synopsis

Abstract

A cell growth factor protein (insulin) and/or a cell‐adhesion protein (fibronectin) were immobilized on surface‐hydrolyzed poly(methyl methacrylate) membranes. The growth of mouse fibroblast cells STO was accelerated by the immobilized insulin. This acceleration was enhanced by introduction of spacer arms. Coimmobilization of insulin and fibronectin was very effective for the acceleration of cell growth. Β© 1993 John Wiley & Sons, Inc.

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