Cell biology of polysialic acid
✍ Scribed by Jozsef Zoltán Kiss; Geneviève Rougon
- Book ID
- 117655814
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 730 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0959-4388
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📜 SIMILAR VOLUMES
## Abstract In this paper we report the first synthesis of novel polysialic acid derivatives which is initiated by treatment of polysialic acid with EDC‐HCl to yield the inter‐residual δ‐lactone. Subsequent reaction with amines or hydrazine gives the corresponding polysialic acid amides and hydrazi
Polysialic acid (PSA) is a long polymer of negatively-charged sialic acid associated with the neural cell adhesion molecule. PSA serves as a potent negative regulator of cell interactions via its unusual biophysical properties. During development the abundant and regulated expression of this carbohy
## Abstract Polysialic acid (PSA) was investigated for its applicability as coating material for mammalian cell cultivation. PSA is involved in post‐translational modification of the vertebrate neural cell adhesion molecule (NCAM). It is biocompatible and degradation‐controlled. Thus, it becomes in