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cDNA Cloning and Functional Expression of a Novel Rat Kidney Organic Cation Transporter, OCT2

โœ Scribed by Masahiro Okuda; Hideyuki Saito; Yumiko Urakami; Mikihisa Takano; Ken-ichi Inui

Book ID
115578728
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
240 KB
Volume
224
Category
Article
ISSN
0006-291X

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โœ Richard M. Green; Kathy Lo; Coreen Sterritt; David R. Beier ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB

Hepatic uptake of organic cations is essential for the metabolism and secretion of numerous endobiotics and drugs. Several hepatic organic cation transporters have been kinetically defined, yet have not been isolated or cloned. We have isolated a complementary DNA (cDNA) from both murine liver and k