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Hormonal regulation of organic cation transporter OCT2 expression in rat kidney

โœ Scribed by Yumiko Urakami; Masahiro Okuda; Hideyuki Saito; Ken-ichi Inui


Book ID
117101824
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
187 KB
Volume
473
Category
Article
ISSN
0014-5793

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The human organic cation transporter 2 (OCT2, SLC22A2) is a multispecific transporter of organic cations, including many clinically used drugs. OCT2 is primarily responsible for the uptake of organic cations across the basolateral membrane of renal tubular epithelial cells and is considered a major