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Molecular cloning and functional expression of a rabbit renal organic cation transporter

✍ Scribed by Shigeyuki Terashita; Mark J. Dresser; Lei Zhang; Andrew T. Gray; Spencer C. Yost; Kathleen M. Giacomini

Book ID
117048846
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
552 KB
Volume
1369
Category
Article
ISSN
0005-2736

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Hepatic uptake of organic cations is essential for the metabolism and secretion of numerous endobiotics and drugs. Several hepatic organic cation transporters have been kinetically defined, yet have not been isolated or cloned. We have isolated a complementary DNA (cDNA) from both murine liver and k