CD4+CD25+ Treg regulate the contribution of CD8+ T-cell subsets in repopulation of the lymphopenic environment
β Scribed by Afonso R. M. Almeida; Ilja F. Ciernik; Federica Sallusto; Antonio Lanzavecchia
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 465 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0014-2980
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In mouse liver transplantation, tolerance is readily inducible. Recent studies have revealed that CD25+ CD4+ regulatory T cells play an important role in regulating various immune responses, including transplant tolerance. However, the contribution of these cells to tolerance in mouse liver transpla