CD4+ T cells and B cells are necessary for the transfer of protective immunity to Plasmodium chabaudi chabaudi
β Scribed by Sally J. Meding; Jean Langhorne
- Book ID
- 102825668
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 573 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0014-2980
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π SIMILAR VOLUMES
The host protective immune response to blood stage malaria infection was studied using Plasmodium chabaudi chabaudi (Echabaudi) in NIH mice. It has been shown previously that CD4+ cells are critically required for protection against erythrocytic infection. Mice lacking a functional CD4+ cell compart
## Isotypic pattern of the polyclonal B cell response during primary infection by Plasmodium chabaudi and in immune-protected mice* The primary infection by P. chabaudi induces an increase of the numbers of splenic immunoglobulin (1g)-secreting B cells in both athymic and euthymic BALBic mice. The
The requirements for maintenance of antigen (Ag)-specific memory T cells in protection to malaria is poorly understood. We have previously demonstrated a recall of IL-4-producing memory CD4 + CD45RO + T cells with parasitized red blood cells (pRBC) in persons protected by radiation-attenuated Plasmo