We describe the first clinical application of T-cell-recruiting bispecific antibodies directly into the tumor without the need to preactivate the effector cells. In a Phase I clinical trial, 10 patients with low-grade B-cell lymphoma were treated by a single locoregional injection of CD3؋CD19 bispec
✦ LIBER ✦
CD3×CD19 bispecific antibodies and CD28 costimulation for locoregional treatment of low-malignancy non-Hodgkin’s lymphoma
✍ Scribed by Oliver Manzke; Sandra Titzer; Hans Tesch; Volker Diehl; H. Bohlen
- Book ID
- 105968255
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 223 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0340-7004
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