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CD28- T cells display features of effector memory T cells in Wegener's granulomatosis

✍ Scribed by Lamprecht, Peter; Mueller, Antje; Gross, Wolfgang L.


Book ID
109066782
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
80 KB
Volume
65
Category
Article
ISSN
0085-2538

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## Abstract ## Objective Accumulating data support the role of regulatory T cells, a subset of CD4+ T cells that expresses CD25^high^ and the transcription factor forkhead box P3 (FoxP3), in controlling and preventing autoimmunity. In Wegener's granulomatosis (WG), an autoimmune vasculitis, up‐reg