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Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis

✍ Scribed by Timme, Terry L; Goltsov, Alexei; Tahir, Salahaldin; Li, Likun; Wang, Jianxiang; Ren, Chengzhen; Johnston, Randal N; Thompson, Timothy C

Book ID: 110063977
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 428 KB
Volume: 19
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1203654

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## Abstract The __MYC__ oncogene is frequently deregulated in human tumors, indicative of a poor prognosis because of enhanced resistance to treatment. In such cases, the cellular sensitivity to chemotherapy could be restored by reactivation of Myc‐driven apoptosis. We have analyzed apoptosis induc