𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Elimination of extrachromosomal c-myc genes by hydroxyurea induces apoptosis

✍ Scribed by T. Petit; K. Davidson; E. Izbicka; D. D. Von Hoff

Book ID
110276026
Publisher
Springer
Year
1999
Tongue
English
Weight
185 KB
Volume
4
Category
Article
ISSN
1360-8185

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Differential regulation of the clusterin
Differential regulation of the clusterin gene by Ha-ras and c-myc oncogenes and during apoptosis
✍ Gerd Klock; Stephan Storch; Jens Rickert; Claudia Gutacker; Claudia Koch-Brandt πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 474 KB πŸ‘ 1 views

Clusterin (ApoJ) is an extracellular glycoprotein expressed during processes of tissue differentiation and regression that involve programmed cell death (apoptosis). Increased clusterin expression has also been found in tumors, however, the mechanism underlying this induction is not known. Apoptotic

Down-regulation of c- myc and bcl-2 gene
Down-regulation of c- myc and bcl-2 gene expression in PU.1-induced apoptosis in murine erythroleukemia cells
✍ Fumiko Kihara-Negishi; Toshiyuki Yamada; Yoshiko Kubota; Nobuo Kondoh; Hitomi Ya πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 223 KB πŸ‘ 3 views

We found that over-expression of PU.1, a member of the ets family of transcription factors, induces apoptotic cell death along with differentiation of DMSO stimulation in murine erythroleukemia (MEL) cells. To elucidate the molecular mechanisms of apoptosis, cell-cycle distribution and expression of

Downregulation of the c-MYC target gene,
Downregulation of the c-MYC target gene, peroxiredoxin III, contributes to arsenic trioxide-induced apoptosis in acute promyelocytic leukemia
✍ Pablo E. Vivas-MejΓ­a; Bulent Ozpolat; Xian Chen; Gabriel Lopez-Berestein πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 484 KB

## Abstract Arsenic trioxide (ATO) induces differentiation and apoptosis in acute promyelocytic leukemia (APL). Several reports indicate that in APL cells apoptosis occurs mainly by a mechanism that involves the inhibition of glutathione peroxidase, one of the enzymes that regulates mitochondrial l