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Cationic peptide antimicrobials induce selective transcription of micF and osmY in Escherichia coli

✍ Scribed by Joon-Taek Oh; Yolanda Cajal; Ewa M. Skowronska; S. Belkin; Junghuei Chen; Tina K. Van Dyk; Myron Sasser; Mahendra Kumar Jain


Book ID
117049298
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
306 KB
Volume
1463
Category
Article
ISSN
0005-2736

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A fusion protein was genetically engineered that contains an antimicrobial peptide, designated P2, at its carboxy terminus and bovine prochymosin at its amino terminus. Bovine prochymosin was chosen as the fusion partner because of its complete insolubility in Escherichia coli, a property utilized t