𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cationic Mixed Micelles in the Presence of β-Cyclodextrin: A Host–Guest Study

✍ Scribed by Mandeep Singh Bakshi

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
91 KB
Volume
227
Category
Article
ISSN
0021-9797

No coin nor oath required. For personal study only.

✦ Synopsis

The conductances of trimethyltetradecylammonium bromide (TTAB) + triphenyltetradecylphosphonium bromide (TTPB) and TTAB + trimethylhexadecylammonium bromide (HTAB) over the entire mole fraction range of TTAB (α TTAB ) were measured in water and in β-cyclodextrin + water (CD + W) mixtures at fixed 4 and 8 mM of CD at 30 • C. The conductivity plots for both binary mixtures show a single break from which the mixed critical micelle concentration (cmc) and degree of micelle ionization (χ ) were computed. From the slopes of the conductivity curves, the equivalent ionic conductivities of the monomeric ( m ), associated ( ass ), and the micelle ( mic ) states were calculated and discussed with respect to the surfactant-CD complexation in the whole mole fraction range of both surfactant binary mixtures. The association constant (K) between the respective monomeric surfactant and CD cavity of fixed 4 mM CD was computed by considering 1 : 1 association from the surface tension measurements. A comparison among the K values for HTAB-CD, TTAB-CD, and TTPB-CD shows that the former complexation is significantly stronger in comparison to the other ones due to the longer hydrophobic tail. The nonideality in mixed micelle formation in pure water was evaluated by using the regular solution theory, and it was observed that both binary mixtures exhibit close to ideal behavior.

📜 SIMILAR VOLUMES

α-Cyclodextrin Host–Guest Binding: A Com
α-Cyclodextrin Host–Guest Binding: A Computational Study of the Different Driving Forces
✍ Sereina Riniker; Xavier Daura; Wilfred F. van Gunsteren 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 400 KB 👁 1 views

Free-energy differences govern the equilibrium between bound and unbound states of a host and its guest molecules. The understanding of the underlying entropic and enthalpic contributions, and their complex interplay are crucial for the design of new drugs and inhibitors. In this study, molecular dy

NMR characterization of the host–guest i
NMR characterization of the host–guest inclusion complex between β-cyclodextrin and doxepin
✍ Jennifer R. Cruz; Bridget A. Becker; Kevin F. Morris; Cynthia K. Larive 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 403 KB

## Abstract The interaction between doxepin, a member of the tricyclic antidepressant (TCA) class of drugs, with β‐cyclodextrin (β‐CD) was investigated using NMR. Several TCAs have been reported to form a complex with β‐CD having 1:1 stoichiometry. Previous results from UV‐visible spectroscopy, flu

Synthesis of β-Cyclodextrin Containing C
Synthesis of β-Cyclodextrin Containing Copolymer via “Click” Chemistry and Its Self-Assembly in the Presence of Guest Compounds
✍ Jianxiang Zhang; Kristin Ellsworth; Peter X. Ma 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 612 KB

## Abstract We report the synthesis of a hydrophilic copolymer with one polyethylene glycol (PEG) block and one β‐cyclodextrin (β‐CD) containing block by a “click” reaction between azido‐substituted β‐CD and propargyl flanking copolymer. ^1^H NMR study suggested a highly efficient conjugation of β‐

Cyclodextrins in Polymer Synthesis: Enzy
Cyclodextrins in Polymer Synthesis: Enzymatic Polymerization of a 2,6-Dimethyl-β-Cyclodextrin/2,4-Dihydroxyphenyl-4′-Hydroxybenzylketone Host-Guest Complex Catalyzed by Horseradish Peroxidase (HRP)
✍ Lorenzo Mejias; Dieter Schollmeyer; Silvia Sepulveda-Boza; Helmut Ritter 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB

## Abstract This paper reports the enzymatic polymerization of the inclusion complex 2,4‐dihydroxyphenyl‐4′‐hydroxybenzylketone/2,6‐dimethyl‐__β__‐cyclodextrin by horseradish peroxidase (HRP) in aqueous media. The structure of the complex was determined by means of NOESY‐NMR and crystallographic an