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Cationic Liposome-Mediated Gene Delivery to the Liver and to Hepatocellular Carcinomas in Mice

✍ Scribed by Mohr, Leonard; Yoon, Seung-Kew; Eastman, Simon J.; Chu, Q.; Scheule, Ronald K.; Scaglioni, Pier P.; Geissler, Michael; Heintges, Tobias; Blum, Hubert E.; Wands, Jack R.

Book ID
124100031
Publisher
Mary Ann Liebert
Year
2001
Tongue
English
Weight
799 KB
Volume
12
Category
Article
ISSN
1043-0342

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Liposome-mediated extracellular superoxi
Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice
✍ Jian Wu; Li Liu; Roy D. Yen; Andreea Catana; Michael H. Nantz; Mark A. Zern πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 302 KB

Our previous study demonstrated that polycationic liposomes are highly stable in the bloodstream and represent an effective agent for liver gene delivery. We report here that liposomemediated extracellular superoxide dismutase (EC-SOD) gene delivery successfully prevented acute liver injury in mice.