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Poly(cationic lipid)-mediated in vivo gene delivery to mouse liver

✍ Scribed by Liu, L; Zern, M A; Lizarzaburu, M E; Nantz, M H; Wu, J


Book ID
110039163
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
938 KB
Volume
10
Category
Article
ISSN
0969-7128

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## Background: One of the main drawbacks of synthetic, non-viral gene vectors is their relatively low in vivo efficiency when compared with viral vectors. the present paper describes the use of a partially fluorinated glycerophosphoethanolamine (f-pe), a close analog of dope, which, as a helper lip