Cathelicidin family of antimicrobial pep
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Ann Eisenberg Shinnar; Kathryn L. Butler; Hyon Ju Park
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Article
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2003
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Elsevier Science
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English
β 211 KB
Cathelicidins are a gene family of antimicrobial peptides produced as inactive precursors. Signal peptidase removes the N-terminal signal sequence, while peptidylglycine a-amidating monooxygenase often amidates and cleaves the C-terminal region. Removal of the cathelin domain liberates the active an