The effect of increasing single oral doses of the novel catechol-O-methyltransferase (COMT) inhibitor, nitecapone, on enzyme activity in red cells (RBC) and gastroduodenal COMT activity has been studied in healthy male volunteers. A dose-dependent decrease in RBC COMT activity was seen in all cases
β¦ LIBER β¦
Catechol-O-methyltransferase: variation in enzyme activity and inhibition by entacapone and tolcapone
β Scribed by C. De Santi; P. C. Giulianotti; A. Pietrabissa; F. Mosca; G. M. Pacifici
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 330 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0031-6970
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