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Catechol-o-methyltransferase (COMT) is associated with negative symptoms of schizophrenia

✍ Scribed by Q. Xu; Y. Fan; Y. Wang; Y. Shen

Book ID: 118439746
Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 43 KB
Volume: 23
Category: Article
ISSN: 0924-9338
DOI: 10.1016/j.eurpsy.2008.01.914

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Several linkage studies suggested chromosome 22q11-13 may harbor susceptible genes for schizophrenia. Catechol-0methyl-transferase t:COMT), which is involved in the metabolism of catecholamines, was mapped to 22q'll and is considered a possible candidate gene for schizophrenia. Recently, we identifi