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Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment

โœ Scribed by Gupta, Meenal; Bhatnagar, Pallav; Grover, Sandeep; Kaur, Harpreet; Baghel, Ruchi; Bhasin, Yasha; Chauhan, Chitra; Verma, Binuja; Manduva, Vallikiran; Mukherjee, Odity


Book ID
111882400
Publisher
Future Medicine
Year
2009
Tongue
English
Weight
480 KB
Volume
10
Category
Article
ISSN
1462-2416

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Several linkage studies suggested chromosome 22q11-13 may harbor susceptible genes for schizophrenia. Catechol-0methyl-transferase t:COMT), which is involved in the metabolism of catecholamines, was mapped to 22q'll and is considered a possible candidate gene for schizophrenia. Recently, we identifi