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Catalytic Mechanism of Hamster Arylamine N -Acetyltransferase 2 †

✍ Scribed by Wang, Haiqing; Liu, Li; Hanna, Patrick E.; Wagner, Carston R.

Book ID
126401676
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
202 KB
Volume
44
Category
Article
ISSN
0006-2960

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Recent evidence suggests that 5-aminosalicylate acts as an anti-inflammatory agent by virtue of its ability to act as a free-radical scavenger. The major metabolite, N-acetyl-5-aminosalicylate is not an effective freeradical scavenger. We have demonstrated that an arylamine N-acetyltransferase from