Catalytic Highly Enantioselective 1,3-Dipolar Cycloaddition Reaction of Nitrones with 3-Alkenoyl-2-oxazolidinones by Use of a Bidentate Chiral Bis(imine) Ligand—Cu(II) Triflate Complex.
✍ Scribed by Takao Saito; Takuya Yamada; Shingo Miyazaki; Takashi Otani
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 27 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract Using the __C__~2~‐symmetric bis‐oxazoline copper(II) catalyst **6f** as a chiral Lewis acid, α′‐phosphoric enones **2** undergo 1,3‐dipolar cycloaddition with nitrones **3** to provide isoxazolidines **4** with very high enantioselectivity and __endo/exo__ selectivity.
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