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Catalytic Enantioselective Michael Addition in the Synthesis of α-Aminophosphonates.

✍ Scribed by Zsuzsa M. Jaszay; Gabor Nemeth; Truong Son Pham; Imre Petnehazy; Alajos Gruen; Laszlo Toeke


Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract A quinine‐promoted, enantioselective Michael addition reaction of diphenyl phosphite with nitroalkenes has been developed. This methodology affords a facile access to enantiomerically enriched β‐nitrophosphates, precursors for the preparation of synthetically and biologically useful β‐a