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Quinine-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroolefins (I): Synthesis of Chiral Precursors (III) of α-Substituted β-Aminophosphonates.

✍ Scribed by Jian Wang; Lora D. Heikkinen; Hao Li; Liansuo Zu; Wei Jiang; Hexin Xie; Wei Wang


Publisher
John Wiley and Sons
Year
2007
Weight
27 KB
Volume
38
Category
Article
ISSN
0931-7597

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Quinine-Catalyzed Enantioselective Micha
✍ Jian Wang; Lora D. Heikkinen; Hao Li; Liansuo Zu; Wei Jiang; Hexin Xie; Wei Wang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB 👁 2 views

## Abstract A quinine‐promoted, enantioselective Michael addition reaction of diphenyl phosphite with nitroalkenes has been developed. This methodology affords a facile access to enantiomerically enriched β‐nitrophosphates, precursors for the preparation of synthetically and biologically useful β‐a