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Catalytic Enantioselective Intermolecular Cycloaddition of 2-Diazo-3,6-diketoester-Derived Carbonyl Ylides with Alkynes and Styrenes Using Chiral Dirhodium(II) Carboxylates

โœ Scribed by Shimada, Naoyuki; Anada, Masahiro; Nakamura, Seiichi; Nambu, Hisanori; Tsutsui, Hideyuki; Hashimoto, Shunichi


Book ID
127345619
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
176 KB
Volume
10
Category
Article
ISSN
1523-7060

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Catalytic enantioselective intermolecula
โœ David M. Hodgson; Agnรจs H. Labande; Rebecca Glen; Alison J. Redgrave ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 194 KB

Catalytic enantioselective tandem carbonyl ylide formation-cycloaddition reactions of tert-butyl 2-diazo-3,6-dioxoheptanoate 7 with alkyne and strained alkene dipolarophiles to afford the corresponding cycloadducts with up to 92% ee are described.