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Catalytic Asymmetric Synthesis of α-Alkylidene-β-hydroxy Esters via Dynamic Kinetic Asymmetric Transformation Involving Ba-Catalyzed Direct Aldol Reaction

✍ Scribed by Yamaguchi, Akitake; Matsunaga, Shigeki; Shibasaki, Masakatsu


Book ID
126258467
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
272 KB
Volume
131
Category
Article
ISSN
0002-7863

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## Abstract An easily available and efficient chiral __N__,__N__′‐dioxide–nickel(II) complex catalyst has been developed for the direct catalytic asymmetric aldol reaction of α‐isothiocyanato imide with aldehydes which produces the products in morderate to high yields (up to 98 %) with excellent di