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Catalytic Asymmetric Synthesis of 3-(α-Hydroxy-β-carbonyl) Oxindoles by a ScIII-Catalyzed Direct Aldol-Type Reaction

✍ Scribed by Ke Shen; Xiaohua Liu; Ke Zheng; Wei Li; Xiaolei Hu; Lili Lin; Xiaoming Feng


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
344 KB
Volume
16
Category
Article
ISSN
0947-6539

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## Abstract An easily available and efficient chiral __N__,__N__′‐dioxide–nickel(II) complex catalyst has been developed for the direct catalytic asymmetric aldol reaction of α‐isothiocyanato imide with aldehydes which produces the products in morderate to high yields (up to 98 %) with excellent di