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Catalytic Asymmetric Synthesis of Palmerolide A via Organoboron Methodology

โœ Scribed by Penner, Marlin; Rauniyar, Vivek; Kaspar, Ludwig T.; Hall, Dennis G.


Book ID
121239503
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
416 KB
Volume
131
Category
Article
ISSN
0002-7863

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Catalytic enantioselective syntheses of the macrolides (R)-(-) phoracantholide and (R)-(+) lasiodiplodin have been achieved. Stereochemistry was introduced in using an arene chromium tricarbonyl derived catalyst, which mediated the enantioselective addition of dimethyl zinc to a functionalized aldeh