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Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

โœ Scribed by Camps, M.

Book ID
121159519
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
412 KB
Volume
280
Category
Article
ISSN
0036-8075

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The observation that mitogen-activated protein (MAP) kinases ERK1 and ERK2 are constitutively activated in a number of oncogene-transformed cell lines has led to the hypothesis that prolonged activation of these enzymes is required for the transformation process. To investigate this question, we hav