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Catalytic Reaction Pathway for the Mitogen-Activated Protein Kinase ERK2

✍ Scribed by Prowse, Claudine N.; Hagopian, Jonathan C.; Cobb, Melanie H.; Ahn, Natalie G.; Lew, John

Book ID
127039329
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
8 KB
Volume
39
Category
Article
ISSN
0006-2960

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## Abstract **Background:** Extracellular signal‐regulated kinase 2 (ERK2) has been implicated in cell proliferation, differentiation, and survival. However, its role __in vivo__ remains to be determined. **Results:** Here we show that the targeted disruption of the mouse ERK2 gene results in embr